Welcome

• Welcoming Remarks
  William Jeffrey, PhD, Director, NIST
• Belinda Seto, PhD
  Deputy Director
  National Institute of Biomedical Imaging and Bioengineering, NIH
• Larry G. Kessler, ScD
  Director, Office of Science and Engineering Laboratories
  Center for Devices and Radiological Health, FDA

Session 1:  Standards Needs from Public Private Partnerships
Focus:   Imaging as a Biomarker -- Sources of Image Variability in the Measurement of Change Over Time
Session Chair:  Larry Clarke, PhD, NCI

• Alzheimer's Disease Neuroimaging Initiative 
  (Michael W. Weiner, MD, ADNI)
• Osteoarthritis Initiative (OAI)
  (Charles Peterfy, MD, SYNARC)
• Reference Image Database to Evaluate Response (RIDER) and Related Oncology Biomarker Initiatives
  (Larry Clarke, PhD, NCI)
• FDA Perspective – The Necessity for Standardization of Imaging in Multicenter Clinical Trials for Investigational Drugs & Biologics
  (George Mills, MD, FDA)

Session 2:  Stakeholder Perspectives
Session Chair:  Mostafa Analoui, PhD Pfizer

• Pharmaceutical Research & Manufacturers of America
  (Mostafa Analoui, PhD, Pfizer)
  
• Radiological Society of North America
  (R. Gilbert Jost, MD, President-elect RSNA)
• American College of Radiology
  (Mitch Schnall, MD, PhD, Chair-elect ACRIN)
• American Association of Physicists in Medicine
  (Jim Purdy, PhD, ATC, AAPM)
• Society for Nuclear Medicine
  (Sandy McEwan, MD, President-Elect SNM)
• IT and Architectures for Imaging Biomarkers
  (Michael Hehenberger, PhD, IBM Healthcare & Life Sciences)
• Contract Research Organizations
  (David A. Clunie, MD, Chief Technology Officer, RadPharm)

Session 3:  Concurrent Breakout Sessions

Goals for Breakout Sessions --  Linda Beth Schilling, NIST

Day 1 --  Big Picture Roadmapping – The What by When?
Day 2 --  Detailed Measurement Science & Standards Needs – The What by When and by Who?

Adjourn to Breakout Rooms

• Big Picture Roadmapping – The What by When

Concurrent Breakout Sessions (Breakout includes discussions of other emerging imaging modalities)

• Area #1:  X-Ray & X-Ray CT:  What can be measured over time?                    
  (Disease models:  Lung Cancer, Bone Imaging and Osteoarthritis)
  (Charles Peterfy, MD, Chair)
• Area #2:  PET & PET CT:  What can be measured over time?                           
  (Disease models:  Alzheimer’s Disease and Lung Cancer)
  (Paul Kinahan, PhD, Chair)
• Area #3:  MRI, MRS, DCE and Diffusion MRI:  What can be measured over time? 
  (Disease models:  Cardiology, Oncology, Osteoarthritis)
  (Jeffrey L. Evelhoch, PhD, Chair)
• Area #4:  Open architecture and software tools:  Image and meta-data collection and analysis, data integration and display
  (Larry Tarbox, PhD, Chair)
• Area #5:  Resources for qualification of imaging systems, benchmarking of image processing and data integration tools, and related statistical methods
  (Nick Petrick, PhD, Chair)
• Area #6:  Data archival and access methods: Image, related meta-data and clinical outcome data, related data interoperability standards, and innovative methodologies for data interpretation
  (Mike Vannier, MD, Chair)

Session 4:  Chair Reports from Breakout Sessions (10 min each)

• Area #1:  X-Ray & X-Ray CT
• Area #2:  PET & PET CT
• Area #3:  MRI, MRS, DCE and Diffusion MRI
• Area #4:  Open Architecture and software tools
• Area #5:  Qualification of imaging systems
• Area #6:  Data archival and access method

Session 6:  Medical Imaging-Integrated Solutions
Session Chair:  Andrew Whitman, VP NEMA Medical

Company Perspectives:  (15 – 20 min each)

• Jonathan Allis, PhD  --  GE Healthcare
• David Rollo, MD  --  Philips Medical Systems
• Heinrich Kolem, PhD   --  Siemens Medical Solutions

Audience Q&A Moderated by Session Chair (15 - 30 min)

Session 7:  Concurrent Breakout Sessions  (same topic areas cont’d)
Detailed Measurement Science & Standards Needs –The What, by When and by Whom?

• Area #1:  X-Ray & X-Ray CT
• Area #2:  PET & PET CT
• Area #3:  MRI, MRS, DCE and Diffusion MRI
• Area #4:  Open Architecture and software tools
• Area #5:  Qualification of imaging systems
• Area #6:  Data archival and access methods

Lunch – NIST Cafeteria

NOTE: All afternoon sessions to be held in the Red Auditorium.

Session 8:  Chair Reports from Breakout Sessions   (15 min + 5 min Q&A each)

• Area #1: :  X-Ray & X-Ray CT
• Area #2 :   PET & PET CT
• Area #3 :   MRI, MRS, DCE and Diffusion MRI

Session 8:  Chair Reports from Breakout Sessions (cont’d)
(15 min + 5 min Q&A each)

• Area #4:  Open Architecture and software tools
• Area #5   Qualification of imaging systems
• Area #6:  Data archival and access methods